Description

5-(4-Chlorobutyl)-1-Cyclohexyltetrazole-D11 is a deuterated derivative of a tetrazole-based compound, serving as a critical stable isotope-labeled intermediate. Its primary value lies in enabling advanced analytical and research applications where precise molecular tracking is essential. This product is specifically needed by pharmaceutical R&D laboratories and contract research organizations (CROs) for use in drug metabolism and pharmacokinetics (DMPK) studies, as well as in the development of analytical reference standards.

Application

• Internal Standard for LC-MS/MS: Used as a high-purity, stable isotope-labeled internal standard in quantitative bioanalytical methods for accurate mass spectrometry analysis.
• Drug Metabolism Studies (DMPK): Critical for tracing the metabolic fate of parent drug compounds in preclinical and clinical research.
• Pharmacokinetic Research: Enables precise measurement of drug absorption, distribution, metabolism, and excretion (ADME) profiles.
• Reference Standard Development: Serves as a certified reference material (CRM) for method validation and quality control in analytical laboratories.
• Isotope Dilution Mass Spectrometry (IDMS): Employed in this gold-standard technique for achieving high accuracy and precision in quantitative analysis.
• Proteomics and Metabolomics Research: Facilitates relative and absolute quantification in complex biological sample analysis.

Basic Information

Product Name	5-(4-Chlorobutyl)-1-Cyclohexyltetrazole-D11
CAS No.	1073608-19-1
Molecular Formula	C11H9D11ClN4
Molecular Weight	Contact for details
Synonyms	1-Cyclohexyl-5-(4-chlorobutyl)tetrazole-D11; 5-(4-Chlorobutyl)-1-cyclohexyl-1H-tetrazole-D11; Tetrazole-D11 derivative; Deuterated Chlorobutyl Cyclohexyltetrazole; Stable Isotope Labeled Tetrazole; D11-Labeled Tetrazole Intermediate; [D11]-5-(4-Chlorobutyl)-1-Cyclohexyltetrazole
EINECS	Contact for details

Quality Control

Our deuterated compounds are manufactured under strict quality control protocols to ensure exceptional isotopic purity and chemical integrity. Each batch is characterized using advanced analytical techniques including NMR (for deuterium incorporation) and HPLC/MS. A comprehensive Certificate of Analysis (COA) is provided, detailing assay, isotopic enrichment, and impurity profiles to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment. For long-term stability, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (NMR/MS)	≥ 98.0 atom % D
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.