Description

Pf 04554878 Hydrochloride is a high-purity, non-natural amino acid derivative designed for advanced pharmaceutical research and development. This compound serves as a critical building block or intermediate in the synthesis of novel therapeutic agents, particularly in targeted drug discovery programs. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require reliable, high-quality intermediates for complex synthetic routes.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs) for preclinical and clinical development.
• Proteomics & Biochemistry Research: Used in the study of enzyme mechanisms, protein-protein interactions, and metabolic pathways.
• Peptidomimetic Development: Serves as a specialized amino acid analog for creating peptide-like molecules with enhanced stability and bioavailability.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and lead optimization for new drug candidates.
• Bioconjugation: Utilized as a linker or functional handle for attaching payloads, labels, or other molecules in bioconjugate chemistry.
• Academic & Contract Research: Supplied to universities and CROs for fundamental chemical biology research and custom synthesis projects.

Basic Information

Item	Details
Product Name	Pf 04554878 Hydrochloride
CAS No.	1073160-26-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	PF-04554878 HCl; (2S,4S)-1-[(2S)-2-Amino-3,3-dimethylbutanoyl]-4-[(3S)-2-oxopyrrolidin-3-yl]pyrrolidine-2-carboxylic acid hydrochloride; 1-[(2S)-2-Amino-3,3-dimethylbutanoyl]-4-[(3S)-2-oxopyrrolidin-3-yl]-L-proline hydrochloride; PF 04554878 hydrochloride salt; PF04554878 HCl
EINECS	Contact for details

Quality Control

Our Pf 04554878 Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (NMR, MS), to ensure it meets the stringent requirements for research and development use. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under inert conditions or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.