Description

(S)-1-(5-Fluoropyridin-2-Yl)Ethanamine Hydrochloride is a high-purity chiral amine building block, essential for the synthesis of novel active pharmaceutical ingredients (APIs) and agrochemicals. Its value lies in its defined stereochemistry and the reactive amine group, which serves as a key handle for constructing complex molecular architectures. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for drug discovery, process development, and the production of advanced intermediates.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the development of new small-molecule drugs, particularly in therapeutic areas targeting the central nervous system (CNS) and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where its fluoropyridine moiety can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating chiral ligands and organocatalysts used in asymmetric synthesis to control stereoselectivity.
• Chemical Biology Research: Employed as a molecular probe or a building block for labeling compounds in biochemical and pharmacological studies.
• Custom Synthesis and Contract Manufacturing: A key starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke intermediates for clients.

Basic Information

Product Name	(S)-1-(5-Fluoropyridin-2-Yl)Ethanamine Hydrochloride
CAS No.	1073149-00-4
Molecular Formula	C7H10ClFN2
Molecular Weight	176.62 g/mol
Synonyms	(S)-1-(5-Fluoropyridin-2-yl)ethan-1-amine hydrochloride; (S)-1-(5-Fluoro-2-pyridinyl)ethylamine hydrochloride; (S)-α-Methyl-5-fluoropyridine-2-methanamine hydrochloride; (S)-5-Fluoro-2-(1-aminoethyl)pyridine hydrochloride; (S)-2-(1-Aminoethyl)-5-fluoropyridine hydrochloride; (S)-1-(5-Fluoro-2-pyridyl)ethylamine HCl; (S)-5-Fluoro-PEA hydrochloride (contextual)
EINECS	Contact for details

Quality Control

Our (S)-1-(5-Fluoropyridin-2-Yl)Ethanamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC to confirm enantiomeric purity and standard pharmacopeial methods for identity and assay. A comprehensive Certificate of Analysis (COA) detailing purity, chiral excess, and impurity profiles is provided with every shipment to ensure compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.