Description

3-Fluoro-5-Methylpyridine-4-Boronic Acid is a high-value boronic acid derivative and a versatile building block in modern synthetic chemistry. Its core value lies in enabling the precise construction of complex molecular architectures through reliable cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially in kinase inhibitor and CNS-active compound research.
• Agrochemical Synthesis: Used to create advanced pyridine-based herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Material Science: Serves as a building block for organic electronic materials, such as ligands for OLEDs and charge-transport molecules.
• Chemical Biology & Proteomics: Employed in the development of molecular probes and activity-based protein profiling (ABPP) reagents.
• Ligand Synthesis: Used to prepare sophisticated ligands for catalysis and metal-organic frameworks (MOFs).
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring fluorinated and functionalized pyridine cores.

Basic Information

Product Name	3-Fluoro-5-Methylpyridine-4-Boronic Acid
CAS No.	1072952-44-3
Molecular Formula	C6H7BFNO2
Molecular Weight	154.94 g/mol
Synonyms	(3-Fluoro-5-methylpyridin-4-yl)boronic acid; 4-Borono-3-fluoro-5-methylpyridine; 3-Fluoro-5-methyl-4-pyridineboronic acid; 3-Fluoro-5-methylpyridine-4-boronic acid pinacol ester (common derivative); 3-Fluoro-5-methyl-4-pyridinylboronic acid; 1072952-44-3; 3-Fluoro-5-methylpyridine-4-ylboronic acid
EINECS	Contact for details

Quality Control

Our 3-Fluoro-5-Methylpyridine-4-Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with stringent industry standards. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request to support your regulatory and R&D needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥95% (Typical 97-99%)
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.