Description

(3-(2-Nitrophenoxy)Phenyl)Boronic Acid is a specialized organoboron compound featuring a nitrophenoxy substituent, making it a valuable building block in modern synthetic chemistry. Its primary value lies in its role as a key intermediate in Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex biaryl structures. This high-purity boronic acid is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients, as well as in materials science for creating advanced organic electronic materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of complex drug candidates, particularly those containing biphenyl or heterobiaryl scaffolds via palladium-catalyzed cross-coupling.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides that require specific biaryl motifs for activity.
• Material Science Research: Serves as a monomer or building block for constructing organic semiconductors, liquid crystals, and metal-organic frameworks (MOFs) with tailored electronic properties.
• Chemical Biology & Probe Development: Employed in the creation of molecular probes and sensors that utilize boronic acid chemistry for detecting sugars or other diol-containing molecules.
• Academic & Process R&D: A valuable reagent for methodological development in cross-coupling chemistry and for scaling up synthetic routes in process chemistry.

Basic Information

Product Name	(3-(2-Nitrophenoxy)Phenyl)Boronic Acid
CAS No.	1072945-95-9
Molecular Formula	C12H10BNO5
Molecular Weight	259.03 g/mol
Synonyms	[3-(2-Nitrophenoxy)phenyl]boronic acid; 2-Nitro-3'-boronic acid diphenyl ether; (3-(2-Nitro-phenoxy)-phenyl)-boronic acid; B-[3-(2-Nitrophenoxy)phenyl]boronic acid; 3-(2-Nitrophenoxy)benzeneboronic acid; Boronic acid, B-[3-(2-nitrophenoxy)phenyl]-; 1072945-95-9
EINECS	Contact for details

Quality Control

Our (3-(2-Nitrophenoxy)Phenyl)Boronic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for demanding synthetic applications. Each lot is characterized by advanced analytical techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.