Description

(5-(4-Chlorophenyl)-3H-[1,2,3]Triazolo[4,5-B]Pyridin-3-Yl)(4-(3-(Trifluoromethyl)Phenyl)Piperazin-1-Yl)Methanone CAS NO 1072874-79-3 is a sophisticated heterocyclic compound featuring a triazolopyridine core linked to a substituted piperazine moiety. This molecular architecture is of significant interest for its potential as a key intermediate or active pharmaceutical ingredient (API) in drug discovery programs, particularly in the development of central nervous system (CNS) and oncology therapeutics. It is primarily sought by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in synthesizing novel bioactive molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of potential drug candidates targeting various receptors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize potency and selectivity of lead compounds.
• Biochemical Probe Development: Employed in the creation of tool compounds for investigating biological pathways and target validation.
• CNS Drug Discovery: Its structural features are relevant for research into neurological disorders, potentially acting on serotonin or dopamine receptors.
• Oncology Research: Investigated as a precursor for kinase inhibitors or other targeted cancer therapies.
• Custom Synthesis: Supplied for bespoke chemical synthesis projects requiring high-purity, complex heterocycles.

Basic Information

Product Name	(5-(4-Chlorophenyl)-3H-[1,2,3]Triazolo[4,5-B]Pyridin-3-Yl)(4-(3-(Trifluoromethyl)Phenyl)Piperazin-1-Yl)Methanone
CAS No.	1072874-79-3
Molecular Formula	C24H16ClF3N6O
Molecular Weight	496.87 g/mol
Synonyms	5-(4-Chlorophenyl)-3-{[4-(3-(trifluoromethyl)phenyl]piperazin-1-yl}carbonyl}-3H-[1,2,3]triazolo[4,5-b]pyridine; (5-(4-Chlorophenyl)-3H-[1,2,3]triazolo[4,5-b]pyridin-3-yl)(4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)methanone; Methanone, [5-(4-chlorophenyl)-3H-[1,2,3]triazolo[4,5-b]pyridin-3-yl][4-[3-(trifluoromethyl)phenyl]-1-piperazinyl]-; 1072874-79-3; UNII-9J3F4S8A4B; 9J3F4S8A4B; CHEMBL3185981.
EINECS	Contact for details

Quality Control

Our production of (5-(4-Chlorophenyl)-3H-[1,2,3]Triazolo[4,5-B]Pyridin-3-Yl)(4-(3-(Trifluoromethyl)Phenyl)Piperazin-1-Yl)Methanone adheres to stringent quality protocols suitable for research and development applications. All batches undergo comprehensive analytical characterization to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as HPLC purity, NMR confirmation, and residual solvent levels are provided with each shipment to support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). The product is light-sensitive (store away from light). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.