Description

6-(3,3,3-Trifluoropropoxy)Nicotinic Acid is a high-purity fluorinated nicotinic acid derivative, serving as a critical advanced pharmaceutical intermediate. Its value lies in the unique properties imparted by the trifluoropropoxy group, which can enhance metabolic stability and bioavailability in target molecules. This compound is primarily needed by R&D and production teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where the fluorine moiety can improve efficacy and environmental profile.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Material Science Precursor: Potential intermediate for the development of specialty polymers and advanced materials with specific surface properties.
• Reference Standard: Used as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	6-(3,3,3-Trifluoropropoxy)Nicotinic Acid
CAS No.	1072855-39-0
Molecular Formula	C9H8F3NO3
Molecular Weight	235.16 g/mol
Synonyms	6-(3,3,3-Trifluoropropoxy)pyridine-3-carboxylic acid; Nicotinic acid, 6-(3,3,3-trifluoropropoxy)-; 3-Pyridinecarboxylic acid, 6-(3,3,3-trifluoropropoxy)-; 6-(3,3,3-Trifluoropropoxy)-3-pyridinecarboxylic acid; 6-(3,3,3-Trifluoropropoxy)nicotinate
EINECS	Contact for details

Quality Control

Our 6-(3,3,3-Trifluoropropoxy)Nicotinic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.