Description

At-406 CAS NO 1071992-57-8 is a high-purity, small molecule compound widely utilized in pharmaceutical research and development. This compound serves as a critical intermediate or active pharmaceutical ingredient (API) in the synthesis of novel therapeutic agents. It is primarily sought after by research institutions and pharmaceutical companies engaged in drug discovery, particularly in the fields of oncology and targeted therapies.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of complex drug candidates.
• Kinase Inhibitor Research: Used in biochemical and cellular assays to study and develop inhibitors for specific kinase targets.
• Preclinical Development: Serves as a reference standard or starting material for formulation studies and pharmacokinetic/pharmacodynamic (PK/PD) modeling.
• Chemical Biology Probes: Employed to investigate specific biological pathways and protein functions within disease models.
• API Synthesis: Integral to the scaled-up production of active pharmaceutical ingredients under current Good Manufacturing Practices (cGMP).

Basic Information

Product Name	At-406
CAS No.	1071992-57-8
Molecular Formula	C₂₁H₁₈ClN₅O₂
Molecular Weight	407.85 g/mol
Synonyms	SM-406; Debio 1143; AT-406; (S)-N-((S)-1-(4-Chlorophenyl)ethyl)-2-((S)-2-(methylamino)propanamido)-N-(pyridin-4-ylmethyl)propenamide; XIAP Antagonist AT-406; SM406; Debio1143; Birinapant (related analog)
EINECS	Contact for details

Quality Control

Every batch of At-406 is subjected to rigorous analytical testing to ensure identity, purity, and consistency. Our quality control protocols are designed to meet the stringent requirements of pharmaceutical R&D and are supported by comprehensive documentation. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with specifications for HPLC purity, water content, residual solvents, and heavy metals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccator after opening to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.