Description

(S)-1-(6-(Trifluoromethyl)Pyridin-3-Yl)Ethanamine is a high-value chiral amine building block featuring a trifluoromethylpyridine scaffold. This compound matters for its role in modern pharmaceutical and agrochemical research, where its unique stereochemistry and fluorine substitution pattern are critical for modulating biological activity, metabolic stability, and lipophilicity. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for the synthesis of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral drug candidates.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances bioactivity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands in asymmetric catalysis, enabling the synthesis of enantiomerically pure compounds.
• Material Science: Incorporated into specialty polymers and advanced organic electronic materials to modify electronic properties and stability.
• Chemical Biology Probe: Utilized in the design of molecular probes and inhibitors for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes under cGMP or ISO standards.

Basic Information

Product Name	(S)-1-(6-(Trifluoromethyl)Pyridin-3-Yl)Ethanamine
CAS No.	1071435-62-5
Molecular Formula	C8H9F3N2
Molecular Weight	190.17 g/mol
Synonyms	(S)-1-[6-(Trifluoromethyl)-3-pyridinyl]ethanamine; (S)-1-(6-(Trifluoromethyl)pyridin-3-yl)ethan-1-amine; (S)-α-Methyl-6-(trifluoromethyl)-3-pyridinemethanamine; (S)-1-(6-(Trifluoromethyl)-3-pyridyl)ethylamine; (S)-1-(6-Trifluoromethylpyridin-3-yl)ethylamine; (S)-6-(Trifluoromethyl)pyridin-3-yl)ethanamine; (S)-TFMP-Ethanamine
EINECS	Contact for details

Quality Control

Our (S)-1-(6-(Trifluoromethyl)Pyridin-3-Yl)Ethanamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting R&D and production standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.