Description

8-Fluoro-2-Phenyl-4-Quinolinol is a fluorinated quinoline derivative, a high-value pharmaceutical intermediate and versatile chemical building block. Its unique structure, featuring both a fluorine atom and a phenolic hydroxyl group, makes it a critical precursor in the synthesis of advanced active pharmaceutical ingredients (APIs) and functional materials. This compound is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science sectors for developing new therapeutic agents and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in oncology, anti-infective, and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, leveraging the bioactivity of the quinoline scaffold.
• Material Science Precursor: Serves as a monomer or functional additive in the creation of advanced polymers, liquid crystals, and organic electronic materials.
• Chemical Synthesis: Employed in organic synthesis as a versatile scaffold for further functionalization via its reactive hydroxyl and fluorine groups.
• Biochemical Research: Utilized as a standard or probe in biochemical assays and pharmacological studies due to its specific fluorinated structure.
• Coordination Chemistry: Acts as a ligand for metal complexes in catalytic and sensing applications.

Basic Information

Product Name	8-Fluoro-2-Phenyl-4-Quinolinol
CAS No.	1070879-73-0
Molecular Formula	C15H10FNO
Molecular Weight	239.25 g/mol
Synonyms	8-Fluoro-2-phenylquinolin-4-ol; 2-Phenyl-8-fluoro-4-quinolinol; 4-Quinolinol, 8-fluoro-2-phenyl-; 8-Fluoro-2-phenyl-4-hydroxyquinoline; 2-Phenyl-8-fluoroquinolin-4-ol; 8-Fluoro-2-phenyl-4(1H)-quinolinone (tautomer); FQ-OH (abbreviation)
EINECS	Contact for details

Quality Control

Our 8-Fluoro-2-Phenyl-4-Quinolinol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be light-sensitive and should be handled accordingly. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.