Description

Bibp 3226 Trifluoroacetate is a high-purity, non-peptide chemical compound used as a potent and selective antagonist for the neuropeptide Y (NPY) Y1 receptor. This specificity makes it a critical research tool for investigating the role of NPY in various physiological and pathological processes. It is primarily utilized by pharmaceutical researchers, contract research organizations (CROs), and academic institutions focused on neuroscience, metabolic disorders, and cardiovascular research.

Application

• Neuroscience Research: Used as a selective NPY Y1 receptor antagonist to study its role in anxiety, depression, stress response, and feeding behavior.
• Metabolic Disorder Studies: Investigated in preclinical research for understanding NPY's influence on obesity, diabetes, and energy homeostasis.
• Cardiovascular Research: Applied in studies exploring NPY Y1 receptor function in blood pressure regulation and vascular tone.
• Drug Discovery & Development: Serves as a key pharmacological reference standard and tool compound for screening and validating new therapeutic candidates targeting the NPY pathway.
• Biochemical Assays: Employed in in vitro binding assays and functional studies to characterize receptor-ligand interactions and signal transduction mechanisms.
• Academic & Institutional Research: Supports fundamental biological research in university and government laboratories worldwide.

Basic Information

Product Name	Bibp 3226 Trifluoroacetate
CAS No.	1068148-47-9
Molecular Formula	C₂₉H₃₀F₃N₃O₃
Molecular Weight	525.57 g/mol
Synonyms	BIBP 3226; BIBP-3226 Trifluoroacetate; (R)-N²-(Diphenylacetyl)-N-[(4-hydroxyphenyl)methyl]-D-argininamide Trifluoroacetate; (R)-N2-(Diphenylacetyl)-N-[(4-hydroxyphenyl)methyl]-D-argininamide Trifluoroacetate; NPY Y1 receptor antagonist BIBP 3226; BIBP3226; BIBP 3226 (TFA); Y1 Receptor Antagonist
EINECS	Contact for details

Quality Control

Our Bibp 3226 Trifluoroacetate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. The product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.