Description

(2-Fluoropyridin-3-Yl)(3-Hydroxypiperidin-1-Yl)Methanone is a high-purity, advanced pharmaceutical intermediate featuring a unique molecular scaffold combining fluoropyridine and hydroxypiperidine motifs. This compound is critical for medicinal chemistry research and development, enabling the synthesis of novel bioactive molecules. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating new drug candidates and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and oncology targets.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR) due to its fluorinated heterocyclic structure.
• Agrochemical Development: Serves as a precursor in the research and synthesis of novel herbicides, fungicides, and insecticides.
• Chemical Biology Probes: Employed in the development of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing specialized fine chemicals.

Basic Information

Product Name	(2-Fluoropyridin-3-Yl)(3-Hydroxypiperidin-1-Yl)Methanone
CAS No.	1065484-91-4
Molecular Formula	C11H13FN2O2
Molecular Weight	224.23 g/mol
Synonyms	1-(2-Fluoropyridine-3-carbonyl)-3-hydroxypiperidine; 3-Hydroxypiperidin-1-yl 2-fluoropyridin-3-yl methanone; (2-Fluoro-3-pyridinyl)(3-hydroxy-1-piperidinyl)methanone; 2-Fluoro-N-(3-hydroxypiperidin-1-yl)nicotinamide; 1065484-91-4; (2-Fluoropyridin-3-yl)(3-hydroxypiperidin-1-yl)methanone
EINECS	Contact for details

Quality Control

Our (2-Fluoropyridin-3-Yl)(3-Hydroxypiperidin-1-Yl)Methanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring high standards, including cGMP and ISO-guided processes for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under dry, inert conditions to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.