Description

1-(3,5-Difluoropyridin-2-Yl)Ethanamine Hydrochloride is a high-purity, fluorinated pyridine derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. It is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific fluorine-substituted motifs into their target molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, especially in kinase inhibitor and central nervous system (CNS) therapeutic research.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the difluoropyridine moiety enhances biological activity and metabolic stability.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Ligand & Catalyst Preparation: Utilized in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Material Science Precursor: Potential intermediate in the synthesis of fluorinated organic electronic materials or liquid crystals.

Basic Information

Product Name	1-(3,5-Difluoropyridin-2-Yl)Ethanamine Hydrochloride
CAS No.	1065267-25-5
Molecular Formula	C7H9ClF2N2
Molecular Weight	194.61 g/mol
Synonyms	1-(3,5-Difluoropyridin-2-yl)ethan-1-amine hydrochloride; 1-(3,5-Difluoro-2-pyridinyl)ethylamine hydrochloride; Ethanamine, 1-(3,5-difluoro-2-pyridinyl)-, hydrochloride (1:1); 2-(1-Aminoethyl)-3,5-difluoropyridine hydrochloride; 1-(3,5-Difluoropyridin-2-yl)ethanamine HCl
EINECS	Contact for details

Quality Control

Our 1-(3,5-Difluoropyridin-2-Yl)Ethanamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.