Description

(3,5-Difluoropyridin-2-Yl)Methanol CAS NO 1065267-14-2 is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both a hydroxymethyl group and strategically placed fluorine atoms, makes it an indispensable intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by R&D and process chemists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the difluoropyridine moiety enhances biological activity and metabolic stability.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of functionalized polymers and liquid crystals, where fluorine substitution modifies electronic and physical characteristics.
• Chemical Biology Probes: Utilized to create fluorescent tags or molecular probes for studying biological systems and drug-target interactions.

Basic Information

Product Name	(3,5-Difluoropyridin-2-Yl)Methanol
CAS No.	1065267-14-2
Molecular Formula	C6H5F2NO
Molecular Weight	145.11 g/mol
Synonyms	2-(Hydroxymethyl)-3,5-difluoropyridine; 3,5-Difluoro-2-pyridinemethanol; (3,5-Difluoropyridin-2-yl)methanol; 2-Pyridinemethanol, 3,5-difluoro-; (3,5-Difluoro-2-pyridinyl)methanol
EINECS	Contact for details

Quality Control

We maintain a stringent quality management system to ensure batch-to-batch consistency and high purity for research and scale-up applications. All batches of (3,5-Difluoropyridin-2-Yl)Methanol are characterized by modern analytical techniques including NMR, HPLC, and GC-MS. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere for long-term storage to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.