Description

(-)-9-Deme-Dtbz CAS NO 1065193-41-0 is a high-purity, stereochemically defined chemical compound used as a key intermediate in advanced pharmaceutical research and development. Its precise molecular structure makes it a critical building block for synthesizing novel active pharmaceutical ingredients (APIs), particularly in the field of neurology and targeted therapeutics. This compound is essential for research institutions, pharmaceutical companies, and contract development and manufacturing organizations (CDMOs) engaged in the synthesis of complex molecules requiring high stereochemical fidelity.

Application

• Pharmaceutical Intermediate: A crucial chiral building block in the multi-step synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Neurological Research: Used in the development and study of compounds targeting specific neurological pathways and receptors.
• Preclinical Development: Serves as a reference standard or starting material for producing compounds used in pharmacological and toxicological studies.
• Process Chemistry: Employed in route scouting and optimization for the scalable production of specialty fine chemicals.
• Academic Research: Utilized in university and institutional labs for methodological development in asymmetric synthesis and medicinal chemistry projects.
• Contract Manufacturing: Supplied to CDMOs for the custom synthesis of client-specific molecules under cGMP or research-grade conditions.

Basic Information

Product Name	(-)-9-Deme-Dtbz
CAS No.	1065193-41-0
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	(-)-9-Demethyl-DTBZ; 9-O-Demethyl-dihydrotetrabenazine; (2R,3R,11bR)-9-Hydroxy-3-isobutyl-10-methoxy-2,3,4,6,7,11b-hexahydro-1H-pyrido[2,1-a]isoquinolin-2-ol; Dihydrotetrabenazine Impurity; DTBZ Related Compound; Tetrabenazine Metabolite Intermediate
EINECS	Contact for details

Quality Control

Our (-)-9-Deme-Dtbz is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chiral purity verification, to meet the stringent requirements of pharmaceutical R&D. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment. We support development with research-grade and can scale to cGMP standards for advanced clinical-stage projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.