Description

Gsk2126458 is a potent and selective small-molecule inhibitor with significant research and development applications. This compound is valued for its high purity and consistent quality, which are critical for reliable experimental results and downstream processes. It is primarily utilized by pharmaceutical researchers, biotechnology companies, and academic institutions engaged in advanced life science studies and drug discovery programs. The product, identified by CAS No. 1065062-66-9, is supplied to meet the stringent demands of the global scientific community.

Application

• Biochemical Research: Used as a key tool compound in enzymatic and cellular pathway studies to investigate specific biological mechanisms.
• Drug Discovery & Development: Serves as a reference standard or active pharmaceutical ingredient (API) intermediate in preclinical research for novel therapeutic agents.
• Pharmacology Studies: Employed in in vitro and in vivo models to assess efficacy, potency, and selectivity profiles.
• High-Throughput Screening (HTS): Utilized in automated assay systems to identify and validate new drug targets.
• Academic Research: Supports fundamental research in universities and institutes focusing on molecular biology and signal transduction.
• Contract Research Organizations (CROs): Supplied to CROs conducting specialized client-sponsored research and development services.

Basic Information

Product Name	Gsk2126458
CAS No.	1065062-66-9
Molecular Formula	C₃₀H₂₃N₅O₃S
Molecular Weight	533.60 g/mol
Synonyms	GSK2126458; GSK '6458; 2,4-Difluoro-N-(2-(methyloxy)-5-(4-(4-pyridazinyl)-6-quinolinyl)-3-pyridinyl)benzenesulfonamide; Omipalisib; PI3K/mTOR Inhibitor GSK2126458
EINECS	Contact for details

Quality Control

Our Gsk2126458 is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity determination and NMR/LC-MS for structural confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We adhere to relevant industry guidelines to support its use in research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants and an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (Mass Spectrometry)	Conforms
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.