Description

4-[[3-(4-Methylphenyl)-3-Oxo-1-(Trifluoromethyl)Propylidene]Amino]Benzenesulfonamide is a specialized organic intermediate featuring a unique trifluoromethylated sulfonamide structure. This compound matters for its role as a critical building block in the synthesis of advanced pharmaceutical and agrochemical agents, where its specific molecular architecture imparts desirable properties to the final product. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting enzymes where the sulfonamide and trifluoromethyl groups are pharmacologically active.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging its structural motifs for enhanced bioactivity and environmental stability.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and the discovery of new bioactive molecules.
• Material Science Applications: Potential building block for advanced polymers or functional materials where its aromatic and fluorinated components can modify physical properties.
• Organic Synthesis Reagent: Employed in specialized organic transformations as a reagent or a protected intermediate due to its reactive functional groups.

Basic Information

Product Name	4-[[3-(4-Methylphenyl)-3-Oxo-1-(Trifluoromethyl)Propylidene]Amino]Benzenesulfonamide
CAS No.	1061214-09-2
Molecular Formula	C18H15F3N2O3S
Molecular Weight	396.38 g/mol
Synonyms	4-[(3-(4-Methylphenyl)-3-oxo-1-(trifluoromethyl)propylidene)amino]benzenesulfonamide; 4-[[3-(4-Methylphenyl)-3-oxo-1-(trifluoromethyl)propylidene]amino]benzenesulfonamide; Benzenesulfonamide, 4-[[3-(4-methylphenyl)-3-oxo-1-(trifluoromethyl)propylidene]amino]-; 1061214-09-2; 4-[(3-(p-Tolyl)-3-oxo-1-(trifluoromethyl)allylidene)amino]benzenesulfonamide; 4-[(Z)-3-(4-Methylphenyl)-3-oxo-1-(trifluoromethyl)prop-1-en-1-yl]benzenesulfonamide
EINECS	Contact for details

Quality Control

Our 4-[[3-(4-Methylphenyl)-3-Oxo-1-(Trifluoromethyl)Propylidene]Amino]Benzenesulfonamide is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with key parameters such as assay (HPLC), related substances, and residual solvents, supporting its use in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials. The container should be kept tightly sealed to protect the contents from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.