Description

5-(3-Methyl-5-Isoxazolyl)-2-Furansulfonyl Chloride (Saltdata: Free) is a high-purity, specialized organic intermediate featuring a unique heterocyclic structure combining isoxazole and furan rings with a reactive sulfonyl chloride group. This compound is critical for the synthesis of novel chemical entities, particularly in advanced pharmaceutical research and agrochemical development. It is primarily utilized by R&D chemists and process development scientists in the life sciences sector for constructing complex molecules with potential biological activity.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially in medicinal chemistry programs targeting new therapeutic agents.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging its heterocyclic scaffold for bioactivity.
• Chemical Biology & Proteomics: Serves as a reactive handle in activity-based protein profiling (ABPP) and the development of covalent enzyme inhibitors due to the sulfonyl chloride moiety.
• Material Science: Potential monomer or cross-linking agent in the synthesis of specialized polymers with unique electronic or thermal properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific custom synthesis projects.

Basic Information

Product Name	5-(3-Methyl-5-Isoxazolyl)-2-Furansulfonyl Chloride (Saltdata: Free)
CAS No.	1060817-75-5
Molecular Formula	C8H6ClNO4S
Molecular Weight	247.66 g/mol
Synonyms	5-(3-Methylisoxazol-5-yl)furan-2-sulfonyl chloride; 2-Furansulfonyl chloride, 5-(3-methyl-5-isoxazolyl)-; 5-(3-Methyl-1,2-oxazol-5-yl)furan-2-sulfonyl chloride; 5-(3-Methyl-5-isoxazolyl)-2-furansulphonyl chloride; 1060817-75-5; 5-(3-Methylisoxazole-5-yl)-2-furansulfonyl Chloride
EINECS	Contact for details

Quality Control

Our 5-(3-Methyl-5-Isoxazolyl)-2-Furansulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support compliance with cGMP, ICH Q7, and REACH regulations for global supply.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.