Description

4-(5-Isoxazolyl)-2-Thiophenesulfonyl Chloride (Saltdata: Free) is a high-purity, specialized organic intermediate designed for advanced pharmaceutical and agrochemical synthesis. This compound is valued for its unique heterocyclic structure, which serves as a critical building block for creating novel active ingredients. It is primarily sought after by research and development teams and production chemists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly those targeting central nervous system (CNS) disorders, infectious diseases, and oncology.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the isoxazole-thiophene scaffold contributes to biological activity.
• Material Science Research: Serves as a precursor for functionalized polymers or organic electronic materials due to its conjugated system.
• Chemical Biology Probes: Employed in the development of molecular probes and enzyme inhibitors for biochemical research.
• Custom Synthesis & Contract Manufacturing: A critical raw material for CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for clients.

Basic Information

Product Name	4-(5-Isoxazolyl)-2-Thiophenesulfonyl Chloride (Saltdata: Free)
CAS No.	1060817-63-1
Molecular Formula	C7H4ClNO3S2
Molecular Weight	249.70 g/mol
Synonyms	4-(1,2-Oxazol-5-yl)thiophene-2-sulfonyl chloride; 5-(2-Thienyl)isoxazole-4-sulfonyl chloride; 4-(5-Isoxazolyl)-2-thiophenesulfonyl chloride; 4-(Isoxazol-5-yl)thiophene-2-sulfonyl chloride; 2-Thiophenesulfonyl chloride, 4-(5-isoxazolyl)-; 1060817-63-1; 4-(1,2-Oxazol-5-yl)thiophene-2-sulfonoyl chloride
EINECS	Contact for details

Quality Control

Our production of 4-(5-Isoxazolyl)-2-Thiophenesulfonyl Chloride (Saltdata: Free) adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity, and is supplied with a detailed Certificate of Analysis (COA). We support cGMP compliance for pharmaceutical applications and can provide stability data and regulatory support documentation upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.