Description

5-[(Methylamino)Carbonyl]-3-Thiophenesulfonyl Chloride (Saltdata: Free) is a high-purity, reactive sulfonyl chloride derivative used as a critical building block in advanced organic synthesis. This compound is essential for introducing the 5-[(methylamino)carbonyl]-3-thiophenesulfonyl moiety into target molecules, enabling the development of novel chemical entities. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating new active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in the development of enzyme inhibitors and receptor modulators.
• Agrochemical Research: Used in constructing active molecules for crop protection agents, such as herbicides and fungicides.
• Material Science: Serves as a precursor for functionalized polymers or advanced materials with specific electronic or surface properties.
• Chemical Biology Probes: Employed in the design and synthesis of activity-based probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: A valuable reagent for custom synthesis houses producing specialized intermediates for client projects.

Basic Information

Product Name	5-[(Methylamino)Carbonyl]-3-Thiophenesulfonyl Chloride (Saltdata: Free)
CAS No.	1060817-61-9
Molecular Formula	C7H6ClNO3S2
Molecular Weight	251.71 g/mol
Synonyms	5-(N-Methylcarbamoyl)thiophene-3-sulfonyl chloride; 3-Thiophenesulfonyl chloride, 5-[(methylamino)carbonyl]-; 5-(Methylcarbamoyl)thiophene-3-sulfonyl chloride; N-Methyl-5-(chlorosulfonyl)thiophene-2-carboxamide; 5-(Methylaminocarbonyl)thiophene-3-sulfonyl chloride; 5-Carbamoylthiophene-3-sulfonyl chloride, N-methyl-; CAS 1060817-61-9
EINECS	Contact for details

Quality Control

Our 5-[(Methylamino)Carbonyl]-3-Thiophenesulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and reactive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and decomposition. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.