Description

C-(5-Trifluoromethoxy-Pyridin-3-Yl)-Methylamine is a high-purity, advanced pharmaceutical intermediate characterized by its pyridine core and trifluoromethoxy substituent. This compound is essential for medicinal chemistry research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs) targeting a range of therapeutic areas. It is a critical building block for pharmaceutical companies, agrochemical research firms, and advanced material scientists seeking to incorporate its unique fluorinated aromatic properties into new molecular entities.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in central nervous system (CNS) and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the trifluoromethoxy group can enhance biological activity and environmental stability.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands in catalytic systems and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic electronic materials.
• Chemical Biology Probes: Utilized to create molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes under cGMP conditions.

Basic Information

Product Name	C-(5-Trifluoromethoxy-Pyridin-3-Yl)-Methylamine
CAS No.	1060815-06-6
Molecular Formula	C8H7F3N2O
Molecular Weight	204.15 g/mol
Synonyms	(5-(Trifluoromethoxy)pyridin-3-yl)methanamine; 3-(Aminomethyl)-5-(trifluoromethoxy)pyridine; 5-(Trifluoromethoxy)-3-pyridinemethanamine; 1-(5-(Trifluoromethoxy)pyridin-3-yl)methanamine; (5-Trifluoromethoxy-pyridin-3-yl)-methylamine; C-(5-Trifluoromethoxy-3-pyridyl)methylamine; 3-Pyridinemethanamine, 5-(trifluoromethoxy)-; 1060815-06-6
EINECS	Contact for details

Quality Control

Our C-(5-Trifluoromethoxy-Pyridin-3-Yl)-Methylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production can adhere to cGMP guidelines for pharmaceutical applications, and we support regulatory filings with necessary documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area%)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.