Description

2-(Chloromethyl)-5-(Trifluoromethoxy)Pyridine is a high-value halogenated pyridine derivative that serves as a critical building block in advanced organic synthesis. This compound matters for its unique molecular architecture, combining a reactive chloromethyl group with a stable trifluoromethoxy substituent, enabling precise chemical modifications. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-infective drugs.
• Agrochemical Synthesis: Building block for developing next-generation herbicides, fungicides, and insecticides with enhanced efficacy and environmental profiles.
• Ligand and Catalyst Development: Used to create novel pyridine-based ligands for transition metal catalysis in fine chemical manufacturing.
• Material Science Research: Intermediate for synthesizing functional polymers and advanced organic electronic materials.
• Custom Synthesis & Contract Manufacturing: Sourced by CDMOs for client-specific projects requiring tailored halogenated heterocycles.
• Life Science Research: Utilized in academic and industrial R&D for probing biological mechanisms and developing chemical probes.

Basic Information

Product Name	2-(Chloromethyl)-5-(Trifluoromethoxy)Pyridine
CAS No.	1060814-93-8
Molecular Formula	C7H5ClF3NO
Molecular Weight	211.57 g/mol
Synonyms	5-(Trifluoromethoxy)-2-(chloromethyl)pyridine; 2-Chloromethyl-5-trifluoromethoxypyridine; 2-Pyridinemethanol, 5-(trifluoromethoxy)-, chloride; 5-(Trifluoromethoxy)-2-pyridinylmethyl chloride; (5-(Trifluoromethoxy)pyridin-2-yl)methyl chloride
EINECS	Contact for details

Quality Control

Every batch of 2-(Chloromethyl)-5-(Trifluoromethoxy)Pyridine is manufactured and tested under a strict quality management system. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles by HPLC, GC, and NMR are available upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (GC)	≥96.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.