Description

2-Bromopyridine-4-Sulfonyl Chloride is a high-purity, reactive chemical intermediate essential for advanced organic synthesis. Its core value lies in its dual functionality, serving as a versatile sulfonylation reagent and a halogenated pyridine building block for constructing complex molecular architectures. This compound is critically needed by researchers and process chemists in the pharmaceutical, agrochemical, and material science industries for the development of new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of sulfonamide-based drug candidates, including kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that require a halogenated pyridine-sulfonyl moiety.
• Material Science Precursor: Employed in the development of functional polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Acts as a reactive handle for labeling proteins or modifying biomolecules in proteomics and bio-conjugation research.
• Cross-Coupling Reactions: Serves as a substrate for palladium-catalyzed coupling reactions (e.g., Suzuki, Stille) to create more complex biaryl systems.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	2-Bromopyridine-4-Sulfonyl Chloride
CAS No.	1060811-61-1
Molecular Formula	C5H3BrClNO2S
Molecular Weight	256.50 g/mol
Synonyms	4-Pyridinesulfonyl chloride, 2-bromo-; 2-Bromo-4-pyridinesulfonyl chloride; 2-Bromopyridine-4-sulfonyl chloride; 2-Bromo-4-(chlorosulfonyl)pyridine; 2-Bromopyridine-4-sulfonchlorid; 2-Bromo-4-sulfonylchloridopyridine; 1060811-61-1 (CAS)
EINECS	Contact for details

Quality Control

Our 2-Bromopyridine-4-Sulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to support your R&D and quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.