Description

2-Methoxy-Pyridine-4-Sulfonyl Chloride is a versatile and reactive organosulfur compound primarily used as a key sulfonylation reagent in organic synthesis. Its value lies in its ability to efficiently introduce the 2-methoxypyridine-4-sulfonyl moiety, a valuable functional group for modulating the properties of target molecules. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of active pharmaceutical ingredients (APIs), especially in the development of kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the sulfonyl chloride group enables the creation of potent bioactive compounds.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D labs for constructing complex heterocyclic compounds and exploring new chemical entities.
• Material Science: Potential applications in the synthesis of functional polymers, ligands for catalysis, and advanced organic materials.
• Custom Synthesis & Contract Manufacturing: Serves as a specialized starting material for custom synthesis projects and scale-up production under cGMP or ISO standards.

Basic Information

Product Name	2-Methoxy-Pyridine-4-Sulfonyl Chloride
CAS No.	1060807-43-3
Molecular Formula	C6H6ClNO3S
Molecular Weight	207.63 g/mol
Synonyms	4-(Chlorosulfonyl)-2-methoxypyridine; 2-Methoxypyridine-4-sulfonyl chloride; 2-Methoxy-4-pyridinesulfonyl chloride; 4-Pyridinesulfonyl chloride, 2-methoxy-; 1060807-43-3
EINECS	Contact for details

Quality Control

Our 2-Methoxy-Pyridine-4-Sulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports applications requiring cGMP and ISO compliance standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.