Description

2,2,2-Trifluoro-1-(6-Methoxypyridin-2-Yl)Ethanone is a high-purity fluorinated pyridine derivative, a key building block in advanced organic synthesis. Its trifluoroacetyl group adjacent to a methoxypyridine scaffold makes it a valuable precursor for developing novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is essential for research and production in pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate fluorine for enhanced bioactivity and metabolic stability.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the trifluoromethyl group improves efficacy and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of fluorinated organic materials and liquid crystals for electronic applications.
• Custom Synthesis and Contract Manufacturing: A key starting material for custom synthesis projects in fine chemical and CDMO (Contract Development and Manufacturing Organization) facilities.

Basic Information

Product Name	2,2,2-Trifluoro-1-(6-Methoxypyridin-2-Yl)Ethanone
CAS No.	1060807-13-7
Molecular Formula	C8H6F3NO2
Molecular Weight	205.14 g/mol
Synonyms	2,2,2-Trifluoro-1-(6-methoxypyridin-2-yl)ethan-1-one; 1-(6-Methoxy-2-pyridinyl)-2,2,2-trifluoroethanone; 6-Methoxy-2-pyridyl trifluoromethyl ketone; 2,2,2-Trifluoro-1-(6-methoxypyridin-2-yl)ethanone; 2-Acetyl-6-methoxypyridine trifluoromethyl ketone; 2-(Trifluoroacetyl)-6-methoxypyridine; 1060807-13-7; 2,2,2-Trifluoro-1-(6-methoxy-2-pyridinyl)ethanone
EINECS	Contact for details

Quality Control

Our 2,2,2-Trifluoro-1-(6-Methoxypyridin-2-Yl)Ethanone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.