Description

3-Fluoro-4-Methoxypyridine is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both fluorine and methoxy substituents, makes it an essential intermediate for creating complex molecules with tailored electronic and steric properties. This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atom enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for constructing specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and electronic materials requiring specific fluorinated aromatic components.
• Chemical Biology Probes: Utilized to create fluorinated analogs of natural products and biochemical tools for mechanism-of-action studies.

Basic Information

Product Name	3-Fluoro-4-Methoxypyridine
CAS No.	1060805-03-9
Molecular Formula	C6H6FNO
Molecular Weight	127.11 g/mol
Synonyms	4-Methoxy-3-fluoropyridine; 3-Fluoro-4-methoxypyridine; 3-Fluoro-4-pyridinol methyl ether; 3-Fluoropyridin-4-yl methyl ether; 4-Pyridinol, 3-fluoro-, methyl ether; 3-Fluoro-4-methoxy-pyridine
EINECS	Contact for details

Quality Control

Our 3-Fluoro-4-Methoxypyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, detailing all critical quality attributes. Our quality commitment aligns with cGMP principles for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider maintaining the material under an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.