Description

2-Fluoro-4-Methylpyridine-3-Carboxylic Acid is a high-value fluorinated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both a carboxylic acid and a fluorine substituent on the pyridine ring, makes it an essential intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for fluorinated drug candidates targeting central nervous system and metabolic diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides where the fluorine atom enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a versatile scaffold for creating novel ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Building block for synthesizing functionalized polymers and advanced organic materials with specific electronic or photophysical properties.
• Chemical Biology Probes: Utilized in the design of molecular probes and tags for studying biological systems and diagnostic applications.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring fluorinated heterocycles.

Basic Information

Product Name	2-Fluoro-4-Methylpyridine-3-Carboxylic Acid
CAS No.	1060804-77-4
Molecular Formula	C7H6FNO2
Molecular Weight	155.13 g/mol
Synonyms	3-Carboxy-2-fluoro-4-methylpyridine; 2-Fluoro-4-methylnicotinic acid; 4-Methyl-2-fluoropyridine-3-carboxylic acid; 2-Fluoro-4-methyl-3-pyridinecarboxylic acid; 1060804-77-4; FMPCA; 2-F-4-Methyl-Pyridine-3-COOH
EINECS	Contact for details

Quality Control

Our 2-Fluoro-4-Methylpyridine-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is sensitive to strong alkalis and fluorides; keep away from incompatible materials. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.