Description

4-Fluoro-3-Hydroxypyridine is a versatile fluorinated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both a fluorine atom and a hydroxyl group on the pyridine ring, makes it a valuable intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-infective agents.
• Agrochemical Synthesis: Used to construct advanced herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in metal-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the development of organic electronic materials and functional polymers.
• Chemical Biology Probes: Utilized to create fluorinated probes for studying enzyme mechanisms and biological pathways.
• Custom Synthesis and Contract Manufacturing: A fundamental building block for custom synthesis projects requiring fluorinated heterocycles.

Basic Information

Product Name	4-Fluoro-3-Hydroxypyridine
CAS No.	1060804-45-6
Molecular Formula	C5H4FNO
Molecular Weight	113.09 g/mol
Synonyms	3-Hydroxy-4-fluoropyridine; 4-Fluoro-3-pyridinol; 4-Fluoropyridin-3-ol; 3-Pyridinol, 4-fluoro-; 4-Fluoro-3-hydroxypyridine; 1060804-45-6
EINECS	Contact for details

Quality Control

Our 4-Fluoro-3-Hydroxypyridine is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We can support development projects requiring material that meets GMP or other stringent regulatory guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.