Description

3-Cyano-Pyridine-4-Sulfonyl Chloride CAS NO 1060804-18-3 is a versatile and highly reactive sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its core value lies in enabling the efficient introduction of the 4-sulfonyl functional group, which is pivotal for creating molecules with tailored biological and physical properties. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of sulfonamide-based drug candidates, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the production of novel herbicides, fungicides, and insecticides that require specific sulfonyl pharmacophores.
• Material Science Research: Employed in the development of functional polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Acts as a reactive handle for labeling proteins or modifying biomolecules in probe development.
• Custom Synthesis & Contract Manufacturing: A fundamental reagent for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	3-Cyano-Pyridine-4-Sulfonyl Chloride
CAS No.	1060804-18-3
Molecular Formula	C6H3ClN2O2S
Molecular Weight	202.62 g/mol
Synonyms	4-Pyridinesulfonyl chloride, 3-cyano-; 3-Cyano-4-pyridinesulfonyl chloride; 3-Cyanopyridine-4-sulfonyl chloride; 4-(Chlorosulfonyl)-3-cyanopyridine; 1060804-18-3; 3-CN-Py-4-SO2Cl
EINECS	Contact for details

Quality Control

Our 3-Cyano-Pyridine-4-Sulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.