Description

3-Fluoro-Pyridine-4-Sulfonyl Chloride is a high-purity, reactive chemical intermediate essential for advanced synthesis. This compound is a critical building block for introducing the 3-fluoro-pyridine-4-sulfonyl moiety into target molecules, enabling the development of novel compounds with specific functionalities. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and crop protection science.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging the pyridine scaffold for bioactivity.
• Material Science Research: Serves as a precursor for creating functionalized polymers, ligands for metal-organic frameworks (MOFs), and other specialty materials.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and tags for studying biological processes and target engagement.
• Custom Synthesis & Contract Manufacturing: A vital reagent for fine chemical manufacturers and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for clients.

Basic Information

Product Name	3-Fluoro-Pyridine-4-Sulfonyl Chloride
CAS No.	1060802-50-7
Molecular Formula	C5H3ClFNO2S
Molecular Weight	195.60 g/mol
Synonyms	4-Pyridinesulfonyl chloride, 3-fluoro-; 3-Fluoro-4-pyridinesulfonyl chloride; 3-Fluoropyridine-4-sulfonyl chloride; 3-Fluoro-4-(chlorosulfonyl)pyridine; 1060802-50-7; 3-Fluoro-4-pyridylsulfonyl chloride; 3-Fluoro-4-sulfonylchloridopyridine
EINECS	Contact for details

Quality Control

Our 3-Fluoro-Pyridine-4-Sulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from strong acids and incompatible organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.