Description

5-Fluoro-Pyridine-2-Sulfonyl Chloride is a high-purity, reactive chemical intermediate essential for advanced organic synthesis. This compound is valued for its role as a versatile sulfonylation reagent, enabling the precise introduction of the 5-fluoro-pyridine-2-sulfonyl moiety into target molecules. It is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing potential drug candidates, particularly in medicinal chemistry programs targeting enzyme inhibition.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its unique fluorinated heterocyclic structure.
• Chemical Biology Probe Development: Employed to create sulfonamide-based probes for studying protein function and biological pathways.
• Material Science Research: Serves as a precursor for functionalized polymers or specialty chemicals with tailored surface properties.
• Custom Synthesis & Contract Manufacturing: A critical reagent for fine chemical manufacturers offering bespoke synthesis services to clients.

Basic Information

Product Name	5-Fluoro-Pyridine-2-Sulfonyl Chloride
CAS No.	1060802-47-2
Molecular Formula	C5H3ClFNO2S
Molecular Weight	195.60 g/mol
Synonyms	2-Pyridinesulfonyl chloride, 5-fluoro-; 5-Fluoropyridine-2-sulfonyl chloride; 5-Fluoro-2-pyridinesulfonyl chloride; 2-Chlorosulfonyl-5-fluoropyridine; 1060802-47-2; 5-Fluoro-2-pyridylsulfonyl chloride
EINECS	Contact for details

Quality Control

Every batch of 5-Fluoro-Pyridine-2-Sulfonyl Chloride is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We ensure compliance with rigorous internal specifications to guarantee identity, purity, and consistency for your synthetic processes. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting key parameters such as assay and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.