Description

4-Chloro-5-Fluoro-2-Pyridinecarbaldehyde is a versatile and highly functionalized pyridine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic positioning of reactive halogen and aldehyde groups, enabling precise molecular construction for complex target molecules. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system disorders, oncology, and infectious diseases.
• Agrochemical Synthesis: Used to construct novel herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the development of organic electronic materials, such as ligands for OLEDs or molecular sensors.
• Custom Synthesis and Contract Manufacturing: A valuable scaffold for custom chemical synthesis services and scale-up projects for clients in life sciences.
• Academic and R&D: Utilized in university and industrial research laboratories for methodological studies and exploring new chemical spaces.

Basic Information

Product Name	4-Chloro-5-Fluoro-2-Pyridinecarbaldehyde
CAS No.	1060802-32-5
Molecular Formula	C6H3ClFNO
Molecular Weight	159.55 g/mol
Synonyms	5-Fluoro-4-chloropyridine-2-carbaldehyde; 2-Pyridinecarbaldehyde, 4-chloro-5-fluoro-; 4-Chloro-5-fluoropicolinaldehyde; 4-Chloro-5-fluoro-2-formylpyridine; 2-Formyl-4-chloro-5-fluoropyridine; 4-Chloro-5-fluoropyridine-2-carboxaldehyde; 1060802-32-5
EINECS	Contact for details

Quality Control

Our 4-Chloro-5-Fluoro-2-Pyridinecarbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring high-purity intermediates under GMP or ISO guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to maintain purity. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.