Description

3-Chloropyridine-4-Sulfonyl Chloride (Wx192259) is a versatile and highly reactive organosulfur compound that serves as a critical building block in advanced chemical synthesis. Its dual functionality as a sulfonyl chloride and a halogenated heterocycle makes it an indispensable reagent for introducing the 3-chloro-4-sulfonylpyridine moiety into target molecules. This intermediate is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients, including potential enzyme inhibitors and receptor modulators. Its precise structure enables the development of compounds with tailored biological activity and physicochemical properties.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in developing sulfonamide-based therapeutics.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that require specific pyridine-sulfonyl scaffolds.
• Chemical Research Reagent: Employed in academic and industrial R&D labs for exploring new reaction pathways and creating specialized chemical libraries.
• Material Science Precursor: Can be utilized in the synthesis of functionalized ligands for catalysts or advanced polymeric materials.
• Sulfonylation Agent: Acts as a reactive sulfonyl chloride for introducing sulfonyl groups into various nucleophiles like amines and alcohols.

Basic Information

Product Name	3-Chloropyridine-4-Sulfonyl Chloride (Wx192259)
CAS No.	1060802-19-8
Molecular Formula	C5H3Cl2NO2S
Molecular Weight	212.05 g/mol
Synonyms	4-Chlorosulfonyl-3-chloropyridine; 3-Chloro-4-pyridinesulfonyl chloride; 3-Chloro-4-sulfonylchloridopyridine; 3-Chloropyridine-4-sulfonic acid chloride; WX-192259; WX192259; 1060802-19-8; Pyridine, 3-chloro-4-sulfonyl chloride
EINECS	Contact for details

Quality Control

Every batch of 3-Chloropyridine-4-Sulfonyl Chloride is produced and tested under strict quality management protocols to ensure consistency and reliability for your synthetic processes. Our standard quality control includes comprehensive analysis using techniques such as HPLC, NMR, and GC to verify identity, purity, and impurity profiles. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical specifications. We adhere to cGMP principles where applicable to support our customers in regulated development pipelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.