Description

2,2,2-Trifluoro-1-(5-(Trifluoromethyl)Pyridin-2-Yl)Ethanone is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring multiple trifluoromethyl groups, is engineered to impart enhanced metabolic stability, lipophilicity, and bioavailability to target molecules. This compound is essential for R&D and production in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), especially in kinase inhibitors, antiviral agents, and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used in the research and manufacture of next-generation herbicides, fungicides, and insecticides, where the fluorine atoms improve efficacy and environmental profile.
• Material Science Precursor: Employed in the synthesis of specialty polymers, liquid crystals, and organic electronic materials requiring fluorinated aromatic units.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Fluorine Chemistry Building Block: Utilized in cross-coupling reactions, nucleophilic substitutions, and other transformations to introduce complex fluorinated motifs.

Basic Information

Product Name	2,2,2-Trifluoro-1-(5-(Trifluoromethyl)Pyridin-2-Yl)Ethanone
CAS No.	1060801-98-0
Molecular Formula	C8H3F6NO
Molecular Weight	243.11 g/mol
Synonyms	1-[5-(Trifluoromethyl)-2-pyridinyl]-2,2,2-trifluoroethanone; 2,2,2-Trifluoro-1-(5-trifluoromethylpyridin-2-yl)ethanone; 2-Acetyl-5-(trifluoromethyl)pyridine, Hexafluoro Derivative; 5-(Trifluoromethyl)-2-pyridyl trifluoromethyl ketone; 2,2,2-Trifluoro-1-(5-(trifluoromethyl)-2-pyridinyl)ethanone; TFMPK Derivative; Hexafluorinated Pyridinyl Ethanone
EINECS	Contact for details

Quality Control

Our 2,2,2-Trifluoro-1-(5-(Trifluoromethyl)Pyridin-2-Yl)Ethanone is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with each shipment, confirming compliance with customer specifications and relevant industry guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.