Description

3-Chloromethyl-5-Trifluoromethyl-Pyridine is a high-value, multi-functional heterocyclic building block characterized by its reactive chloromethyl group and electron-withdrawing trifluoromethyl substituent. This compound is essential for introducing the pyridine core with specific fluorine and chlorine functionalities into more complex molecular architectures. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Ligand and Catalyst Preparation: Serves as a precursor for creating specialized pyridine-based ligands used in catalysis and material science.
• Material Science Research: Employed in the synthesis of functionalized polymers and organic electronic materials.
• Custom Synthesis and Contract Manufacturing: A critical starting material for fine chemical manufacturers offering bespoke synthesis services.

Basic Information

Product Name	3-Chloromethyl-5-Trifluoromethyl-Pyridine
CAS No.	1060801-94-6
Molecular Formula	C7H5ClF3N
Molecular Weight	195.57 g/mol
Synonyms	5-(Trifluoromethyl)-3-pyridinemethanol, chloride; 3-(Chloromethyl)-5-(trifluoromethyl)pyridine; (5-Trifluoromethyl-pyridin-3-yl)-methanol chloride; 3-Pyridinemethanol, 5-(trifluoromethyl)-, chloride; 1060801-94-6; 3-Chloromethyl-5-trifluoromethylpyridine
EINECS	Contact for details

Quality Control

Every batch of 3-Chloromethyl-5-Trifluoromethyl-Pyridine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for research and scale-up activities. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere or in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.