Description

3-Trifluoromethyl-Pyridine-4-Carbaldehyde is a high-purity fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the unique reactivity of the aldehyde group combined with the electron-withdrawing and lipophilicity-enhancing properties of the trifluoromethyl substituent. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients with improved metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitors and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging the trifluoromethyl group for enhanced efficacy.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functionalized polymers and organic electronic materials.
• Chemical Biology Probes: Utilized to create labeled compounds and molecular probes for studying biological systems.

Basic Information

Product Name	3-Trifluoromethyl-Pyridine-4-Carbaldehyde
CAS No.	1060801-92-4
Molecular Formula	C7H4F3NO
Molecular Weight	175.11 g/mol
Synonyms	4-Formyl-3-(trifluoromethyl)pyridine; 3-(Trifluoromethyl)pyridine-4-carboxaldehyde; 3-Trifluoromethyl-4-pyridinecarboxaldehyde; 3-Trifluoromethylisonicotinaldehyde; 4-Pyridinecarboxaldehyde, 3-(trifluoromethyl)-; 3-CF3-Pyridine-4-CHO
EINECS	Contact for details

Quality Control

Our 3-Trifluoromethyl-Pyridine-4-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. This compound is easily oxidized; prolonged exposure to air should be avoided. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.