Description

5-Methoxypyridine-3-Sulfonyl Chloride is a high-purity, reactive sulfonyl chloride derivative used as a key building block in advanced organic synthesis. This compound is valued for its role in introducing the 5-methoxy-3-pyridinesulfonyl moiety, a functional group of significant interest in medicinal chemistry. It is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of potential drug candidates, particularly for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its pyridine-based structure.
• Chemical Biology Probes: Employed in the creation of sulfonamide-based probes and ligands for target identification and protein interaction studies.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers and advanced organic materials.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research organizations for bespoke synthesis projects requiring this specific sulfonylation reagent.

Basic Information

Product Name	5-Methoxypyridine-3-Sulfonyl Chloride
CAS No.	1060801-85-5
Molecular Formula	C6H6ClNO3S
Molecular Weight	207.63 g/mol
Synonyms	3-Methoxy-5-pyridinesulfonyl chloride; 5-Methoxy-3-pyridinesulfonyl chloride; 3-Pyridinesulfonyl chloride, 5-methoxy-; 5-Methoxypyridine-3-sulphonyl chloride; 1060801-85-5
EINECS	Contact for details

Quality Control

Our 5-Methoxypyridine-3-Sulfonyl Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality system is designed to support cGMP compliance for advanced intermediate production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under inert atmosphere or dry conditions to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.