Description

5-Methoxy-Pyridine-2-Sulfonyl Chloride is a high-purity, reactive sulfonyl chloride derivative used as a key building block in advanced organic synthesis. Its primary value lies in its role as a versatile sulfonylation reagent, enabling the introduction of the 5-methoxypyridine-2-sulfonyl moiety into target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of sulfonamide-based drug candidates, including kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that incorporate sulfonyl functional groups.
• Chemical Biology & Proteomics: Serves as a reactive handle for labeling proteins or modifying biomolecules in probe development and activity-based protein profiling (ABPP).
• Material Science Research: Employed in the creation of functionalized polymers and advanced materials with specific sulfonyl-linked properties.
• Custom Synthesis & Contract Manufacturing: A valuable reagent for fine chemical and custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	5-Methoxy-Pyridine-2-Sulfonyl Chloride
CAS No.	1060801-83-3
Molecular Formula	C6H6ClNO3S
Molecular Weight	207.63 g/mol
Synonyms	2-Pyridinesulfonyl chloride, 5-methoxy-; 5-Methoxy-2-pyridinesulfonyl chloride; 5-Methoxypyridine-2-sulfonyl chloride; 5-Methoxy-2-sulfonylchloridopyridine; 1060801-83-3
EINECS	Contact for details

Quality Control

Our 5-Methoxy-Pyridine-2-Sulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and production. Certificates of Analysis (COA) with full batch traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.