Description

3-Methylpyridine-4-Sulfonyl Chloride is a high-purity sulfonyl chloride derivative, a key reactive intermediate in advanced organic synthesis. Its primary value lies in its role as a versatile sulfonylation reagent, enabling the introduction of the 3-methylpyridine-4-sulfonyl moiety to construct complex molecules with targeted properties. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of novel drug candidates, especially in kinase inhibitor and other small-molecule therapeutic programs.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, where the pyridine-sulfonyl group confers specific biological activity.
• Material Science Research: Employed in the creation of functionalized polymers, ligands for catalysis, and advanced organic materials.
• Chemical Biology & Proteomics: Acts as a reactive handle for labeling or modifying biomolecules in probe development and activity-based protein profiling.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research organizations for bespoke chemical synthesis and scale-up projects.

Basic Information

Product Name	3-Methylpyridine-4-Sulfonyl Chloride
CAS No.	1060801-61-7
Molecular Formula	C6H6ClNO2S
Molecular Weight	191.64 g/mol
Synonyms	4-Pyridinesulfonyl chloride, 3-methyl-; 3-Methyl-4-pyridinesulfonyl chloride; 3-Methylpyridine-4-sulfonyl chloride; 3-Methyl-4-sulfonylchloridopyridine; 4-(Chlorosulfonyl)-3-methylpyridine; 3-Picoline-4-sulfonyl chloride
EINECS	Contact for details

Quality Control

Every batch of 3-Methylpyridine-4-Sulfonyl Chloride is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive synthetic applications. A detailed Certificate of Analysis (COA), including results for assay, purity (HPLC), and identification, is supplied with each shipment and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.