Description

4-Bromo-1-(3-Bromopropyl)-2-Fluorobenzene is a specialized halogenated aromatic building block of significant interest in advanced organic synthesis. This compound matters for its unique molecular architecture, featuring both bromine and fluorine substituents on a benzene ring connected to a bromopropyl side chain, which provides multiple reactive sites for selective functionalization. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging the fluorine atom for enhanced biological activity and metabolic stability.
• Liquid Crystal & OLED Material Research: Serves as a building block for creating halogenated aromatic cores used in advanced electronic and display materials.
• Cross-Coupling Reactions: The bromine atoms make it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Fluorine Chemistry Studies: Utilized in academic and industrial R&D to study the effects of fluorine substitution on aromatic systems and reaction pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds for client projects.

Basic Information

Product Name	4-Bromo-1-(3-Bromopropyl)-2-Fluorobenzene
CAS No.	1057678-67-7
Molecular Formula	C9H9Br2F
Molecular Weight	304.0 g/mol
Synonyms	1-Bromo-4-(3-bromopropyl)-2-fluorobenzene; 2-Fluoro-4-bromo-1-(3-bromopropyl)benzene; 4-Bromo-2-fluoro-1-(3-bromopropyl)benzene; 3-Bromopropyl 4-bromo-2-fluorophenyl ether (common misnomer); 1-(3-Bromopropyl)-4-bromo-2-fluorobenzene; Benzene, 4-bromo-1-(3-bromopropyl)-2-fluoro-; (3-Bromopropyl)(4-bromo-2-fluorophenyl) (structural descriptor)
EINECS	Contact for details

Quality Control

Our 4-Bromo-1-(3-Bromopropyl)-2-Fluorobenzene is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, typically ≥97% (by HPLC). Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality system is designed to meet the stringent requirements of pharmaceutical and advanced material research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive nature and organic solvent compatibility, keep away from heat, sparks, and open flames. The container should be kept tightly sealed when not in use to minimize exposure to moisture and prevent volatilization.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.