Description

2-[[9-(1-Methylethyl)-6-[[3-(2-Pyridinyl)Phenyl]Amino]-9H-Purin-2-Yl]Amino]-1-Butanoldihydrochloride is a high-purity, small molecule organic compound of significant interest in advanced pharmaceutical research and development. This compound matters as a key pharmaceutical intermediate or active pharmaceutical ingredient (API) precursor, enabling the synthesis of targeted therapeutic agents. It is primarily needed by pharmaceutical companies, biotechnology research labs, and contract research organizations (CROs) focused on developing novel drug candidates.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the multi-step synthesis of novel drug candidates, particularly in oncology and targeted therapy research.
• Kinase Inhibitor Research: Used as a key precursor or reference standard in the development and screening of potent and selective kinase inhibitors, leveraging its purine-based scaffold.
• Biochemical Assay Development: Employed as a tool compound or ligand in high-throughput screening (HTS) and binding assays to study specific biological pathways and protein interactions.
• Preclinical Studies: Utilized in in vitro and in vivo studies to investigate pharmacokinetics, pharmacodynamics, and initial efficacy of potential therapeutic molecules.
• Reference Standard: Acts as an analytical standard for quality control (QC) and method validation in API manufacturing processes to ensure batch consistency and purity.
• Medicinal Chemistry Optimization: Provides a versatile chemical core for structure-activity relationship (SAR) studies to optimize potency, selectivity, and drug-like properties.

Basic Information

Product Name	2-[[9-(1-Methylethyl)-6-[[3-(2-Pyridinyl)Phenyl]Amino]-9H-Purin-2-Yl]Amino]-1-Butanoldihydrochloride
CAS No.	1056016-06-8
Molecular Formula	C23H28Cl2N8O
Molecular Weight	503.43 g/mol
Synonyms	2-((9-Isopropyl-6-((3-(pyridin-2-yl)phenyl)amino)-9H-purin-2-yl)amino)butan-1-ol dihydrochloride; 1-Butanol, 2-[[9-(1-methylethyl)-6-[[3-(2-pyridinyl)phenyl]amino]-9H-purin-2-yl]amino]-, dihydrochloride; UNII-9R4F8N4N4M; 9R4F8N4N4M; 2-((9-Isopropyl-6-((3-(pyridin-2-yl)phenyl)amino)-9H-purin-2-yl)amino)-1-butanol hydrochloride (1:2); 1056016-06-8 (Parent); Contact for additional aliases.
EINECS	Contact for details

Quality Control

Our 2-[[9-(1-Methylethyl)-6-[[3-(2-Pyridinyl)Phenyl]Amino]-9H-Purin-2-Yl]Amino]-1-Butanoldihydrochloride is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and heavy metals to ensure it meets the stringent requirements for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatograms and spectral data are provided to guarantee traceability and compliance with your internal standards and global regulatory expectations.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the label or COA. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept in a dry environment. For long-term storage, consider desiccants or inert atmosphere to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	< 20 ppm
Assay (on anhydrous basis)	97.0% - 103.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.