Description

2-Oxazol-5-Ylbenzenesulfonyl Chloride is a specialized sulfonyl chloride derivative, a key reactive intermediate in modern organic synthesis. Its primary value lies in its role as a versatile electrophile for constructing sulfonamide linkages, which are critical motifs in advanced chemical development. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of sulfonamide-based drug candidates, including enzyme inhibitors and receptor antagonists.
• Agrochemical Research: Used in developing novel herbicides, fungicides, and insecticides that incorporate the sulfonamide functional group for enhanced activity.
• Material Science: Serves as a monomer or cross-linking agent in the production of specialty polymers and functional materials.
• Chemical Biology & Proteomics: Employed as a reactive handle for labeling proteins or modifying biomolecules to study biological pathways.
• Custom Synthesis & Contract Manufacturing: A valuable reagent for custom synthesis houses and CROs/CMOs producing bespoke compounds for client projects.
• Academic & Industrial R&D: Fundamental research reagent for exploring new synthetic methodologies and reaction mechanisms involving sulfonylation.

Basic Information

Product Name	2-Oxazol-5-Ylbenzenesulfonyl Chloride
CAS No.	1053658-65-3
Molecular Formula	C9H6ClNO3S
Molecular Weight	243.67 g/mol
Synonyms	5-(2-Chlorosulfonylphenyl)oxazole; Benzenesulfonyl chloride, 2-(5-oxazolyl)-; 2-(Oxazol-5-yl)benzenesulfonyl chloride; 2-(1,3-Oxazol-5-yl)benzenesulfonyl chloride; 2-(5-Oxazolyl)benzenesulfonyl chloride; 5-(2-Chlorosulfonylphenyl)-1,3-oxazole
EINECS	Contact for details

Quality Control

Our production of 2-Oxazol-5-Ylbenzenesulfonyl Chloride adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is analyzed using advanced techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.