Description

2,4-Difluorophenylglyoxal Hydrate is a high-purity fluorinated aromatic glyoxal derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a reactive diketone functionality flanked by fluorine atoms, which are essential for modulating the electronic properties and metabolic stability of target molecules. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of fluorinated heterocycles and active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides and fungicides, where the difluorophenyl moiety enhances bioactivity and environmental persistence.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized chelating ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of fluorinated organic electronic materials and advanced polymers.
• Chemical Biology Probes: Useful for synthesizing fluorescent tags and molecular probes that study biological processes.

Basic Information

Product Name	2,4-Difluorophenylglyoxal Hydrate
CAS No.	1049754-94-0
Molecular Formula	C8H6F2O3 • xH2O
Molecular Weight	188.13 (Anhydrous basis)
Synonyms	2,4-Difluorophenylglyoxal Monohydrate; (2,4-Difluorophenyl)-1,2-ethanedione Hydrate; 2,4-DFPG Hydrate; 1,2-Ethanedione, 1-(2,4-difluorophenyl)-, Hydrate; Glyoxal, (2,4-difluorophenyl)-, Hydrate
EINECS	Contact for details

Quality Control

Our 2,4-Difluorophenylglyoxal Hydrate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after use to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.