Description

Erk Inhibitor CAS NO 1049738-54-6 is a potent and selective small molecule inhibitor of Extracellular signal-Regulated Kinase (ERK), a key component of the RAS/RAF/MEK/ERK signaling pathway. This compound is crucial for researchers and developers targeting dysregulated MAPK signaling, which is implicated in various cancers and proliferative diseases. It is primarily utilized in pharmaceutical R&D for drug discovery, preclinical studies, and as a critical biochemical tool in academic and industrial life science laboratories.

Application

• Pharmaceutical Research & Development: Serves as a lead compound or reference standard in the discovery and optimization of novel oncology therapeutics targeting the MAPK pathway.
• Preclinical Cancer Studies: Used in in vitro and in vivo models to investigate tumor biology, validate drug targets, and assess the efficacy of combination therapies.
• Biochemical Pathway Analysis: A essential tool for elucidating the role of ERK signaling in cellular processes such as proliferation, differentiation, and survival.
• High-Throughput Screening (HTS): Employed in assay development and screening campaigns to identify new modulators of the ERK kinase activity.
• Academic Research: Supports fundamental biological research in universities and institutes studying signal transduction mechanisms.
• Biotech Product Development: Used in the development of diagnostic kits and assays related to MAPK pathway activity.

Basic Information

Product Name	Erk Inhibitor CAS NO 1049738-54-6
CAS No.	1049738-54-6
Molecular Formula	C₂₀H₂₀N₈O₂
Molecular Weight	404.43 g/mol
Synonyms	SCH772984; ERK Inhibitor SCH772984; 5-((2-((2-Chloro-4-pyridinyl)amino)-1,3-thiazol-5-yl)methyl)-2,4-pyrimidinediamine; N-(2-Chloro-4-pyridinyl)-5-((2,4-diamino-5-pyrimidinyl)methyl)-1,3-thiazol-2-amine; ERK1/2 Inhibitor SCH772984; Compound SCH772984
EINECS	Contact for details

Quality Control

Our Erk Inhibitor is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with research-grade standards. Specifications are designed to meet the rigorous demands of pharmaceutical and biochemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. This product is hygroscopic (moisture-sensitive). Allow the vial to warm to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.