Description

2-Bromo-1-Iodo-3-(Trifluoromethyl)Benzene is a high-value, multi-halogenated aromatic building block designed for advanced synthetic chemistry. Its unique structure, featuring both bromine and iodine substituents on a trifluoromethylbenzene core, makes it an indispensable reagent for introducing specific halogen functionalities into target molecules. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications such as cross-coupling reactions, fluorinated analog synthesis, and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex, fluorinated drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used to construct novel herbicides, fungicides, and insecticides where the trifluoromethyl and halogen groups enhance biological activity and environmental stability.
• Cross-Coupling Reactions: Serves as a versatile electrophile in Suzuki, Stille, and Negishi couplings, where the iodine and bromine offer differentiated reactivity for sequential functionalization.
• Material Science Research: Employed in the development of organic electronic materials, liquid crystals, and advanced polymers that require specific halogen and fluorine substitution patterns.
• Chemical Biology & Probe Development: Useful for synthesizing fluorinated molecular probes and tags for imaging and diagnostic applications.

Basic Information

Product Name	2-Bromo-1-Iodo-3-(Trifluoromethyl)Benzene
CAS No.	1049731-01-2
Molecular Formula	C7H3BrF3I
Molecular Weight	350.90 g/mol
Synonyms	1-Bromo-2-Iodo-3-(Trifluoromethyl)Benzene; 3-Trifluoromethyl-1,2-Dihalobenzene (mixed halides); 2-Bromo-1-Iodo-α,α,α-Trifluoro-m-Xylene; Benzene, 2-bromo-1-iodo-3-(trifluoromethyl)-; m-(Trifluoromethyl)dibromoidobenzene (isomer specific); Building Block C7H3BrF3I
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-1-Iodo-3-(Trifluoromethyl)Benzene is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for sensitive synthetic applications. A detailed Certificate of Analysis (COA), including results from HPLC, NMR, and GC-MS, is supplied with each shipment to guarantee identity, purity, and lot-to-lot consistency for your research and development processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is light-sensitive (store away from light). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow crystalline solid or liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.