Description

3-Chloro-5-Methylbenzene-1-Sulfonyl Chloride is a versatile and highly reactive organosulfur compound, primarily used as a key sulfonylation reagent and building block in advanced organic synthesis. Its value lies in its ability to introduce the sulfonyl chloride functional group, a crucial precursor for creating sulfonamides, sulfonate esters, and other pharmacologically active motifs. This intermediate is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel sulfonamide-based drug candidates, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides that require the sulfonyl moiety for biological activity.
• Polymer Chemistry: Serves as a monomer or cross-linking agent in the development of specialty polymers, ion-exchange resins, and high-performance materials.
• Dye and Pigment Manufacturing: Acts as an intermediate in the synthesis of sulfonated dyes and organic pigments, enhancing solubility and color properties.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D labs for exploring new synthetic pathways and creating compound libraries.
• Ligand and Catalyst Preparation: Used to functionalize ligands and create novel organocatalysts or metal-organic frameworks (MOFs).

Basic Information

Product Name	3-Chloro-5-Methylbenzene-1-Sulfonyl Chloride
CAS No.	1049026-35-8
Molecular Formula	C7H6Cl2O2S
Molecular Weight	225.09 g/mol
Synonyms	5-Chloro-3-methylbenzenesulfonyl chloride; 3-Methyl-5-chlorobenzenesulfonyl chloride; 1-Chloro-3-methyl-5-sulfonylchloridebenzene; 3-Chloro-5-methylphenylsulfonyl chloride; 3-Chloro-5-toluenesulfonyl chloride; 5-Chloro-m-toluenesulfonyl chloride; m-Toluenesulfonyl chloride, 5-chloro-
EINECS	Contact for details

Quality Control

Our 3-Chloro-5-Methylbenzene-1-Sulfonyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.