Description

2-Fluoro-5-Methylpyridine-3-Carboxylic Acid is a high-value fluorinated pyridine derivative, a key building block in modern synthetic chemistry. Its unique structure, featuring both a carboxylic acid and a fluorine substituent on the pyridine ring, makes it an essential intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, where the fluorine atom enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a versatile scaffold for constructing complex ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the creation of specialty polymers and advanced organic electronic materials due to its electron-withdrawing characteristics.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	2-Fluoro-5-Methylpyridine-3-Carboxylic Acid
CAS No.	1042986-00-4
Molecular Formula	C7H6FNO2
Molecular Weight	155.13 g/mol
Synonyms	3-Carboxy-2-fluoro-5-methylpyridine; 5-Methyl-2-fluoropyridine-3-carboxylic Acid; 2-Fluoro-5-picolinic Acid; 2-Fluoro-5-methylnicotinic Acid; 2-Fluoro-5-methyl-3-pyridinecarboxylic Acid; 1042986-00-4; 2-Fluoro-5-methyl-pyridine-3-carboxylic acid
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-5-Methylpyridine-3-Carboxylic Acid is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and commercial synthesis. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.