Description

5 - Fluoro - 2 - (4 - Methoxy Phenyl) (Acetylene) Benzaldehyde is a high-purity, multi-functional aromatic aldehyde building block featuring a strategically positioned fluoro substituent and an acetylene linker. This compound is critical for advanced organic synthesis, enabling the construction of complex molecular architectures with tailored electronic and steric properties. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for applications such as drug discovery, ligand synthesis, and the development of novel polymers.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and plant growth regulators, leveraging the fluorine atom for enhanced bioactivity and metabolic stability.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the synthesis of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probe Development: The alkyne group enables efficient conjugation via click chemistry (e.g., CuAAC) for labeling proteins, nucleic acids, or creating chemical probes.
• Catalyst & Ligand Synthesis: Employed in the preparation of novel organometallic complexes and chiral ligands for asymmetric catalysis.
• Academic & Contract Research: A valuable reagent for methodological development and exploring new reaction pathways in academic and industrial R&D laboratories.

Basic Information

Product Name	5 - Fluoro - 2 - (4 - Methoxy Phenyl) (Acetylene) Benzaldehyde
CAS No.	1042369-35-6
Molecular Formula	C₁₆H₁₁FO₂
Molecular Weight	254.26 g/mol
Synonyms	5-Fluoro-2-[(4-methoxyphenyl)ethynyl]benzaldehyde; 2-(4-Methoxyphenylethynyl)-5-fluorobenzaldehyde; 5-Fluoro-2-[(4-methoxyphenyl)ethynyl]benzenecarboxaldehyde; 5-Fluoro-2-(4-methoxyphenylethynyl)benzaldehyde; Benzaldehyde, 5-fluoro-2-[(4-methoxyphenyl)ethynyl]-; 1042369-35-6; 5-Fluoro-2-(4-methoxy-phenyl-ethynyl)-benzaldehyde
EINECS	Contact for details

Quality Control

Our 5 - Fluoro - 2 - (4 - Methoxy Phenyl) (Acetylene) Benzaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep the container tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.