Description

2-Chloro-6-(2,2,3,3-Tetrafluoropropoxy)Pyrazine is a specialized fluorinated pyrazine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the unique combination of the pyrazine heterocycle with a chloro and a polyfluorinated alkoxy substituent, enabling precise molecular modifications. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and environmental stability.
• Ligand & Catalyst Development: Serves as a sophisticated ligand scaffold in organometallic chemistry and catalysis for asymmetric synthesis.
• Material Science: Building block for creating fluorinated polymers and liquid crystals with unique electronic and surface properties.
• Chemical Biology Probes: Utilized in the design of molecular probes and tags for studying biological processes and drug-target interactions.

Basic Information

Product Name	2-Chloro-6-(2,2,3,3-Tetrafluoropropoxy)Pyrazine
CAS No.	1039858-65-5
Molecular Formula	C7H5ClF4N2O
Molecular Weight	248.57 g/mol
Synonyms	2-Chloro-6-(2,2,3,3-tetrafluoropropoxy)pyrazine; 2-Chloro-6-(2,2,3,3-tetrafluoropropoxy)-1,4-diazine; 2-Chloro-6-(perfluoropropoxy)pyrazine (common name); 1039858-65-5; Pyrazine, 2-chloro-6-(2,2,3,3-tetrafluoropropoxy)-; 6-Chloro-3-(2,2,3,3-tetrafluoropropoxy)pyrazine (isomer reference)
EINECS	Contact for details

Quality Control

Our 2-Chloro-6-(2,2,3,3-Tetrafluoropropoxy)Pyrazine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support development and commercial projects requiring material meeting GMP or ISO 9001 standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials. The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.