Description

2-Pyridineacetic Acid, A,A-Difluoro- is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring a difluoromethyl group on the acetic acid side chain, makes it an essential precursor for creating novel compounds with enhanced biological activity and metabolic stability. This intermediate is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting enzyme inhibition.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Ligand Synthesis: Serves as a precursor for creating specialized ligands used in catalysis and material science.
• Fluorine Chemistry: A valuable reagent for introducing the difluoromethyl group into complex molecules, a common strategy in modern drug design.
• Academic & Contract Research: Employed in university and CRO laboratories for exploratory synthetic chemistry and method development.
• Fine Chemical Production: Intermediate in the multi-step synthesis of complex, high-value specialty chemicals.

Basic Information

Product Name	2-Pyridineacetic Acid, A,A-Difluoro-
CAS No.	1039621-73-2
Molecular Formula	C7H5F2NO2
Molecular Weight	173.12 g/mol
Synonyms	2,2-Difluoro-2-(pyridin-2-yl)acetic acid; α,α-Difluoropyridine-2-acetic acid; 2-(Pyridin-2-yl)-2,2-difluoroacetic acid; Difluoro(2-pyridyl)acetic acid; 2-Pyridyldifluoroacetic acid; (Pyridin-2-yl)difluoroacetic acid; 2-Pyridineacetic acid, α,α-difluoro-
EINECS	Contact for details

Quality Control

Every batch of 2-Pyridineacetic Acid, A,A-Difluoro- is produced and tested under a strict quality management system to ensure consistency and reliability for your critical applications. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with industry standards. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.